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When active, SKN-1/Nrf2 upregulates the phase II detoxification system, which is also responsible for detoxifying free oxygen radicals [51, 52]

This list is not all-inclusive, but rather suggests that plants and phytochemicals could be a rich source of potential radioprotectants

De Sanctis JB, Balda Noria G, Garca AH (2025) Exploring how adipose tissue, obesity, and gender influence the immune response to vaccines: a comprehensive narrative review

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Possible molecular mechanisms involved in MTX-induced intestinal injury and mechanisms of actions of protective agents are graphically illustrated in Fig