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AML is characterized by the accumulation and blocked differentiation of progenitors of myeloid, monocytic, erythroid, or megakaryocytic lineage, and ALL instead arises from the transformation of B-cell (B-ALL) or T-cell progenitors (T-ALL) ( Although the use of various chemotherapy schemes for the treatment of ALs has achieved a high percentage of survival in developed countries, in Colombia its implementation has shown discouraging results, with complete remission rates of 45% in AML and 61% in ALL in the adult population (Sossa et al., 2021)

Deletion of TRAP1 leads to impaired mitochondrial function and increased sensitivity to stress [107]

Dey S, Murmu N, Mondal T, Saha I, Chatterjee S, Manna R, Haldar S, Dash SK, Sarkar TR, Giri B (2022) Multifaceted entrancing role of glucose and its analogue, 2-deoxy-D-glucose in cancer cell proliferation, inflammation, and virus infection

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Growth hormone secretion follows a circadian rhythm with the largest pulse occurring 6090 minutes after sleep onset