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Issues such as poor bioavailability, rapid metabolism, and limited bloodbrain barrier permeability hinder the therapeutic application of polyphenols

[DOI] [PMC free article] [PubMed] [Google Scholar] 22.Paavola A, Kurppa K, Ukkola A, Collin P, Lahdeaho ML, Huhtala H, Maki M, Kaukinen K

Apoptosis detection (Biolegend) was conducted using a BD FACS Canto II flow cytometer

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doi: 10.5607/en20011 103 KinouchiR.TakedaM.YangL.WilhelmssonU.LundkvistA.PeknyM.et al

Overall, KD shows promise as a complementary therapeutic strategy capable of targeting multiple aspects of PD pathology