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SPB Academic, The Hague, pp 109123 Berthe-Corti L, Hulsch R, Nevries U, Eckardt-Schupp F (1992) Use of batch and fed-batch fermentation for studies on the variation of glutathione content and its influence on the genotoxicity of methyl-nitro-nitrosoguanidine in yeast

Reducing oxidative stress through a healthy lifestyle is also important

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Because FDX1 also delivers Cu(I) required for cuproptotic lipoylated-protein clustering, fluctuations in Fe-S availability (reflected by ISCU2, LIAS or FDX1 levels) simultaneously report mitochondrial iron sufficiency and dictate whether excess copper triggers death or is safely buffered by the Fe-S-centered respiratory chain (Wang et al

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Together, these coordinated processes strengthen the erythrocytes adaptive response to hypoxia by enhancing its capacity to release oxygen where it is most needed