interaction of chloroacetamide electrophiles with cellular glutathion An Activity-Guided Map Electrophile-Cysteine Interactions in Primary Human T Cells: Cell Glutathione dynamics in subcellular compartments
Glutathione dynamics in subcellular compartments and implications for drug development ScienceDirect Identification, optimization, and structural elucidation of chloroacetamide scaffold as covalent inhibitors for Ubiquitin C terminal Hydrolase L3 bioRxiv Expanding the Chemistry of Dihaloacetamides as Tunable Electrophiles for Reversible Covalent Targeting of Cysteines Journal of Medicinal Chemistry Systematic cysteine scanning identifies a druggable pocket in oncogenic KRAS: Cell Chemical Biology Targeting a Therapy Resistant Cancer Cell State Using Masked Electrophiles as GPX4 Inhibitors bioRxiv General concept of unsaturated PVelectrophiles in Cysselective Download Scientific Diagram
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