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doi: 10.1016/j.mce.2011.03.011 74 FretzJAZellaLAKimSShevdeNKPikeJW

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BPC-157 angiogenic mechanism: Increases VEGF expression triggering endothelial cell proliferation, migration, and tube formation

Still, even these hypothetical neuroimaging studies would remain descriptive and they would have to be complemented by new experimental animal models as well as post-mortem studies to discover novel potentially drug-able molecular targets

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In this study in rats, low doses of withaferin A were shown to have a cardioprotective effect by upregulating the mitochondrial anti-apoptotic pathway due to an increase in AMP-activated protein kinase (AMPK) phosphorylation and an increase in the Bcl-2/Bax ratio (AMPK) [54]