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News Release July 12, 2007 ConsumerLab.com finds lutein & zeaxanthin supplements vary widely in strength but most meet ingredient claims Right amount of antioxidant may help prevent macular degeneration and improve vision WHITE PLAINS, NEW YORK July 12, 2007 ConsumerLab.com announced today that all but one of the thirteen lutein and zeaxanthin supplements it recently chose to test met quality standards

partial sequence of human Body Protection Compound Sequence: H-Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val-OH (GEPPPGKPADDAGLV) Synonyms: PL 14736, PLD-116 CAS Number: 137525-51-0 Molecular Formula: C 62 H 98 N 16 O 22 Molecular Weight: 1419.55 g/mol Mechanism (working): modulation of nitric oxide system, VEGFR-2 expression, and growth factor signaling supporting GI, vascular, and connective-tissue repair Regulatory status: not approved by the FDA or EMA TB-500 Compound class: synthetic N-acetylated heptapeptide

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Steroid Biochem.1986, 25 (5), 867-876 72

this suggests a detrimental Th2 response related to age, rather than ADE of disease 113

Patients were instructed to use high dose vitamin B12 nasal drops (5,000 mcg one nasal drop in each nostril, twice per week)