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Transcriptome analysis of microglia isolated from SOD1 G93A mice revealed increases in activated pro-inflammatory Igf1 , Progranulin, Trem2 , cytokines, and neurotoxic factor MMP-12 (Chiu et al., G93A and SOD1 L8Q stimulate Rac1-GTP activation of NOX and the production of ROS, unlike WT SOD1 (Boille et al., M1 microglial cells are also activated by inflammatory stimuli

PUVA inhibits DNA replication, but not gene transcription ay nonlethal dosages

These drugs are widely used to treat locally advanced or metastatic breast, colorectal, head and neck cancer, among others

Gosti, F., N

doi: 10.3390/ijms262110558 32 CaiH.ShenC.XuH.QianH.PeiS.CaiP.et al