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Other targeted molecules Other molecules such as human telomerase reverse transcriptase (hTERT), ATRX and protein kinase C, have also gained attention as potential targets for GBM cancer therapy

The study also included a catalytically inactive C145A M pro mutant (lacking the active site cysteine), which was also used as a bait protein, in order to discriminate false positives that might bind non-specifically to the M pro active site cysteine via disulfide bond formation

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Tew KD, Monks A, Barone L, Rosser D, Akerman G, Montali JA, Wheatley JB and Schmidt Jr DE

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