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doi: 10.1016/j.freeradbiomed.2022.12.008

GST catalyzes the conjugation of glutathione on the sulfur atom of cysteine to various electrophiles and catalyses the conjugation of various electrophiles with GSH, detoxifying both exogenously and endogenously derived toxic compounds [13]

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Recommended Monitoring Steps Obtain ALT, AST, GGT, and total bilirubin at baseline before isotretinoin initiation