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Toxicol In Vitro 2007

Variants in MTHFR, MTRR, and COMT shape baseline methylation and B12 metabolism, the pathways MIC-B12 acts on

2 Endocrine complications Pituitary hormone deficiencies are among the major long-term consequences of CO CP [13]

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Comparison of TVX-induced toxicity in 2D cultured HepaRG and 3D liver models demonstrated a slightly higher decrease in viability in 3D models when treated with 20 m TVX