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The majority of AR binding sites (ARBSs) are found in enhancer and intergenic regions rather than in gene promoters, and long-distance interactions occur via chromatin looping between AR bound at AREs at different regions (enhancers versus promoters) of the same AR target gene [53]

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Moreover, the commitment to myogenic lineage and inhibition of adipogenic lineage by androgenic treatment was reversed dose-dependently by bicalutamide incubation, highlighting that cell commitment here was regulated through AR

Helps support cognitive function in the elderly subpopulation