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Disclosures: Iyiad Alabdul Razzak: Nothing to Disclose, Gloria Horta: Nothing to Disclose, Xinyuan Zhang: Nothing to Disclose, Paolo Lopedote: Nothing to Disclose, Xuehong Zhang: Nothing to Disclose, Michelle Lai: Nothing to Disclose 2283 THE FRAILTY COMPONENT OF HEPATIC ENCEPHALOPATHY - EXPLORING PHYSICAL AND COGNITIVE FUNCTION IN ADVANCED CHRONIC LIVER DISEASE Andres Duarte-Rojo 1 Miguel Sogbe 2 Randi Wong 3 Robert Rahimi 4 Pamela Bloomer 5 Alexandra Steinberg 6 Jennifer Lai 3 , 1 Northwestern Medicine, 2 Universidad de Navarra, 3 UCSF, 4 Baylor University Medical Center, 5 UPMC, 6 Axcella Health, Inc Background: Physical frailty and minimal hepatic encephalopathy (MHE) are common in advanced chronic liver disease (AdvCLD)

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