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10.1016/j.devcel.2021.10.006 Dev

Tanabe, K

The instability and high reactivity of Fe 2+ lead to the generation of hydroxyl radicals from excess iron by means of the Fenton reaction

We introduced these concepts in a perspective review [7]

Accumulating evidence has established butyrate as a key epigenetic regulator of ubiquitin signaling networks, particularly influencing protein homeostasis in cellular antioxidant systems and ferroptosis pathways