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Therefore, inducing cellular cuproptosis to promote DAMP release and ICD, while disrupting the TME and converting suppressive cold tumors into immune cell-active hot tumors, thereby impairing tumor cell viability, has become a new direction for intervening in cancer progression (Wang et al., 2024a)

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it's absolutely essential for maximizing research outcomes

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The following types of vectors were used: pDEST17 (N-terminal His-tag), pDEST15 (N-terminal GST-tag), pDEST24 (C-terminal His-tag), pDEST42 (C-terminal GST-tag)

We will commence by presenting the biological underpinnings of NF-B signaling and elucidate the mechanisms of its self-regulation and crosstalk with other pathways