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doi: 10.1016/S1369-5266(00)00199-0 31 EbertAW

Cultivating fungal research

Reported side effects are generally mild and include temporary gastrointestinal discomfort, headaches during initial use, occasional fatigue as the body adjusts, and rare nausea, especially when taken without food

These above concepts and results contrast the established role of PDH kinase 1 (PDK1) in supporting tumor growth downstream of hypoxia-inducible factor (HIF) signaling by suppressing PDH activity [20-22]