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Results Anti-nitrative effect of trisulfides as an introductory part of the study Given the potent anti-oxidative functions of GSSSG and LASSS, the first set of experiments was designed to examine if these trisulfides have potential to prevent peroxynitrite-induced nitration-dysfunction of HGF by ECL-Western blotting (see Figure 1a for the in vitro experimental design)

Voucher is non-transferable

PHN alone or also to local irritators , and whether optimized medication, physical therapy/desensitization, nerve/sympathetic blocks, or (rarely) RF/neuromodulation are appropriate

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For the measurement of lipid peroxidation the method of 40 was followed

Construction of further hTrxR1 variants On the basis of the information provided by the crystal structure of the complex, 3 hTrxR1 mutants were produced from the hTrxR1 U498C mutant described above (hTrxR1 W114A,U498C , hTrxR1 N419A,U498C , and hTrxR1 W407A,N418/9A,U498C )