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Cell (2016) 167(3):829842 e13

ALS may manifest double onset: involvement of the extremities (80% of cases) or bulbar involvement (20% of cases) (Parakh et al., 2013)

K.ItohK.YamamotoM.KenslerT

C.VeeckmansG.TyurinaY

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This comprehensive immune response translates to potent antitumor effects, establishment of long-term immune memory against the tumor, and aligns perfectly with the evolving paradigm of immunotherapy, which seeks to integrate preventive and therapeutic strategies