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151,152 H 2 S and cancer: beyond disturbed metabolism In addition to the energetic stimulus afforded by low H 2 S concentrations, the link between the adaptability of cancer cells to an evolving and challenging environment and enhanced H 2 S metabolism extends to adaptation to hypoxia, antioxidant capacity, neoangiogenesis, cell cycle regulation, apoptosis evasion and chemoresistance

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Sphingosine-1-phosphate promotes the nuclear translocation of -catenin and thereby induces osteoprotegerin gene expression in osteoblast-like cell lines

Consistently, we assessed the labile iron pool (LIP) following PA treatment using calcein-AM fluorophore, which quenches in the presence of Fe 2+/3+ , and found that the LIP was increasing in the presence of PA in a dose-dependent manner