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doi: 10.1007/978-3-031-96852-5

2023;24:132 Li JM, Yang DC, Oldham J, Linderholm A, Zhang J, Liu J, et al

Mutations in IDH cause the loss of its enzymatic activity of converting isocitrate to -KG while conferring a neo-enzymatic activity of reducing -KG to the oncometabolite D-2-hydroxyglutarate, an excess of which favors the formation of malignant tumors (86)

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Additionally, major adaptive trials like the RECLAIM study are currently evaluating WPI as a primary intervention arm for lingering post-COVID cardiovascular and fatigue symptoms

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