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Georgiades, F., Hosgood, S

Despite advances in supportive care for survivors and improvements in anti-inflammatory interventions and treatments that inhibit the inflammatory process in lungs, the morbidity and mortality of ALI remains higher than acceptable [6]

The increase in the secretion of inflammatory mediators and the reduction of anti-inflammatory factors will further aggravate the immune response, leading to more serious disease progression [17], an effect confirmed by a significantly imbalanced Th17/Treg cell ratio in AR patients [18]

Serasanambati M, Chilakapati SR

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It consists of the enzymatic transfer of a methyl group (-CH 3 ) to the carbon-5 position of the cytosine base within the cytosine-guanine (CpG) dinucleotide, leading to the formation of 5-methylcytosine (5mC) [12]