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Motif overlap with pTyr-binding proteins Tyr kinase signalling networks frequently involve the recruitment of multiprotein complexes through modular domains that recognize and bind to the amino acid sequence surrounding a central pTyr residue 17,18

The metabolomic difference between different generations PDX with chemotherapy treated was obvious Since important tumor-related metabolisms, such as TCA, can undergo reprogramming during the establishment and passage of PDX models, it is critical to investigate whether there are differences in the chemosensitivity and post-chemotherapy tumor metabolism among PDX models with different passages

HMGB1 upregulates TFR1 expression via Ras-JNK/p38 pathways, promoting ferroptosis (Ye et al., 2019)

Glutathione: One of the most powerful antioxidants your body makes

As shown in Figure 4B , HY5 exhibited strong binding to the wild-type MYB4 promoter fragment, however not to the mutated one