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Data from animal and human studies show that apigenin is quite safe at high doses and no toxicity has been reported [256, 257]

doi: 10.1186/s12905-021-01320-6 13 BertiF

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Antioxidant Protection: Glutathione is a powerful antioxidant that protects skin cells from damage caused by free radicals and environmental stressors

GR was co-expressed with G6PD and GPX at protein level, which indicated that glutamine peroxidase and GSSH acted synergistically in glutamine synthesis pathway