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Thus, all spectral properties of roGFP2 are fully retained in the newly-generated roGFP2-iL

10.1002/jcp.28910 50 GentricG.KiefferY.MieuletV.GoundiamO.BonneauC.NematiF.et al (2019)

This process may facilitate the release of various mitochondrial components and their metabolic byproducts, which possess immunogenic characteristics, such as mitochondrial DNA (mtDNA) and cytochrome C, into the cytoplasm

5 Evidence indicates that patients with TED produce autoantibodies that stimulate this receptor complex, causing hyperactivation of orbital fibroblasts and immune cells which mediate the disease process in susceptible individuals