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Description

Hofbauer LC, Heufelder AE

Genetic abnormalities in Band 3, as observed in hereditary spherocytosis and Southeast Asian ovalocytosis, result in morphologically abnormal cells characterized by reduced flexibility and shortened life span due to increased splenic clearance (1)

Excessive iron in the internal environment can cause ferroptosis in ovarian GCs, which slows oocyte maturation and follicle development, increasing the risk of infertility (106, 107)

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Some allelic variants are present in all populations, while others are exclusive to a particular ethnic group or have a highly variable frequency [53, 54, 55]

Somatostatin (SST) mRNA expression in the hypothalamus was markedly increased in the treatment group, whereas SST receptor (SSTR)-2 mRNA expression in the pituitary gland was decreased