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Science, 324 , 10291033

This oxidative damage originating from neurons can induce neuroinflammation and gliosis through the release of DAMPs

The soothing efficacy is also backed up by multiple in-vivo studies

On another aspect, pretreatment with SSA was found to reduce the glutamate level in the hippocampus of rats by influencing glutamate and aspartate transporter (GLAST) in the PTZ model [64]