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Organoid-derived intestinal epithelial cells are a suitable model for preclinical toxicology and pharmacokinetic studies

Mol Neurobiol 47:632644 Paolicelli RC, Bolasco G, Pagani F, Maggi L, Scianni M, Panzanelli P, Giustetto M, Ferreira TA, Guiducci E, Dumas L, Ragozzino D (2011) Synaptic pruning by microglia is necessary for normal brain development

Cancers 2023;15:2901

Regulated exocytosis in astrocytic signal integration

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For vascular maturation, lysyloxidase (LOX) is critical, and copper can modulate LOX production through ATOX1, ATP7A and Ras-related C3 botulinum toxin substrate 1 (RAC1) (51)