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Accumulation of ROS plays a crucial role in the pathogenesis of cardiomyopathy, leading to myocardial fibrosis, ventricular remodelling and direct damage to cardiomyocytes (74)

[PubMed Citation] N-acetylcysteine (NAC), as a thiol compound, often acts as an antioxidant or reactive oxygen species (ROS) scavenger to prevent lung injury in animal models

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c , BN-PAGE immunoblot on isolated WAT mitochondria from Control and Bmal1-KO mice at ZT14 using an antibody mix against OXPHOS complex subunits (n = 4)

doi: 10.3390/cancers12113150 178 XuBZhuWJPengYJChengSD

Adamson IY, Young L, Bowden DH (1988) Relationship of alveolar epithelial injury and repair to the induction of pulmonary fibrosis