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Albers GJ, Michalaki C, Ogger PP, Lloyd AF, Causton B, Walker SA

Binding kinetics and thermodynamics, autophagy induction, apoptosis, and self-renewal were evaluated via isothermal titration calorimetry, Western blotting, annexin V assays, and tumorsphere formation assays, whereas aptamer-cell interaction and intracellular drug accumulation were quantified using flow cytometry

In the mouse model, integrin 3 expression peaks during WOI, and if this increase is blocked, implantation is significantly inhibited with decreased embryo implantation number [64]