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However, studies have shown a correlation between the administration of -carotene supplements and the risk of bladder cancer, as well as the risk of lung cancer in smokers (Lin et al., 2009)

doi: 10.1038/nrrheum.2017.10 71 RosserECOleinikaKTononSDoyleRBosmaACarterNAet al

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Establishment of K7M2-Luc orthotopic osteosarcoma mouse model and therapeutic effect evaluation Tumor model establishment To establish orthotopic model, K7M2 cells (3 10 6 cells/well) were dispersed in PBS buffer and implanted into right tibia of BALB/c mice