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(60) utilized next generation sequencing (NGS) and computational analysis to demonstrate that miR-23b-3p, acting as a tumor suppressor, can inhibit tumor Gln metabolism by targeting GLS1, thereby enhancing the sensitivity of liver tumor cells to sorafenib

Pilarczyk B, Balicka-Ramisz A, Ramisz A, Adamowicz E, Pilarczyk R, Tomza-Marciniak A, Bkowska M (2009) Selenium concentration in liver and kidney of free living animals (roe and red deer) from West Pomerania (Poland)

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Is hypoxia the cause or effect of tumors

Intracellular iron is stored in two major formsan unstable intracellular free ferrous iron pool and an inert form bound to ferritin ( 2 can trigger the Fenton reaction, producing ROS ( 4.2.2 Iron metabolism Transferrin-bound trivalent iron binds to the transferrin receptor (TFR1), allowing direct cellular entry through endocytosis and converts it to ferrous iron through STEAP3

Accumulation of SAH can impair transmethylation reactions by allosteric inhibition of methyltransferases