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The Wnt/-catenin pathway exerts its effects through key components such as Wnt ligands, Frizzled receptors, -catenin, and TCF/LEF transcription factors, which collectively regulate various cellular functions (74)

Altogether, these data will have to be firmly established by complementary experiments, especially if a cleavage could also generate soluble isoforms

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doi: 10.1093/bja/78.4.352 [DOI] [PubMed] [Google Scholar] 91.Jang DH, Weaver MD, Pizon AF