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Cannabinoid hyperemesis syndrome (CHS) happens when you have cycles of nausea, vomiting and abdominal pain from long-term pot use

In males, nicotine affects the testes where prolonged exposure changes the morphology of spermatogenic cells, reduces sperm production, decreased steroidogenesis and inhibits spermatogenesis resulting in decreased sperm counts, poor sperm motility and increased levels of DNA damage [20, 21]

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Now, some shops are playing a more subtle time-gap game : Mixed batches: Mixing new and old pods and selling them together, so you cant tell from the packaging

Nicotine and tar residue transfer onto the skin during cigarette smoking or handling tobacco products, leading to a noticeable yellowish discolouration