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doi: 10.7717/peerj.16594 117 SuSWChenXWangGLiPYangTXFangKWet al

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High-grade gliomas like glioblastoma multiforme (GBM) exhibit especially robust neutrophil infiltration, and these TANs have been implicated in tumor progression and recurrence (72, 75, 76)

While less than 1% of patients experience cardiac toxicity, 50% of patients who experience a cardiac event discontinue immunotherapy due to the high mortality rate

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