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doi: 10.1128/AEM.68.9.4672-4675.2002, 214 ShahidM.KhanM

Most of these studies have suggested clinically relevant reductions in migraine frequency and severity, but are limited by lack of placebo control (four out of seven studies)

PMID: 92 ZhouQMWangSZhangHLuYYWangXFMotooYet al

The final cost may change if the infection is deeper than expected, if intravenous antibiotics are required, if an abscess needs drainage, if additional tests are needed, or if underlying conditions require closer monitoring.