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Transition metals with two contiguous oxidation states, typically Fe and Cu, but also Co and Ni, are able to catalytically convert endogenous, naturally produced hydrogen peroxide into the hydroxyl radical through radical-chain mechanisms such as that long known as the Fenton reaction [12] (Scheme 2)

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Wehrli, PhD, study principal investigator and professor of Radiologic Science and Biophysics, Perelman School of Medicine, University of Pennsylvania Research from the National Institutes of Health (NIH) found that long-term use of e-cigarettes can impair blood vessel function in ways similar to, or worse than, regular cigarettes

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