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[13], the black line represents pharmacokinetic profile of the dosage form on the Y-axis, the blue line is diurnal variation of young men between the ages of 23 and 28 years of age and the yellow line represents the diurnal variation of older men between the ages of 58-82 years of age

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Glutamate released by astrocytes surrounding the synaptic cleft is believed to be more prone to induce excitotoxicity by acting on extrasynaptic NMDA receptors [17, 18]

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