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Selenium and Glutathione Peroxidase Function Selenium serves as an essential cofactor for glutathione peroxidase, one of the primary enzymes that utilizes glutathione to neutralize hydrogen peroxide and lipid peroxides

Zhai Y, Li O, Qi R, Zhang H, Ji XK, Li H

On the other hand, the redox imbalance in favor of the prooxidants results in an overproduction of the ROS/RNS leading to oxidative stress

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The Canadian Hydroxychloroquine Study Group

Ringel et al., 2021), and IgM natural antibodies, TLR inhibitors, modulators of cellular components (neutrophils, basophils, eosinophils, mast cells, monocytes, macrophages, dendritic cells, regulatory T cells, natural killer cells) of innate immunity, cellular components of both innate and adaptive immune systems ( T cells, natural killer T cells), soluble constituents of adaptive immunity (polyreactive IgM antibodies to the viral disease, among others), and cellular components of adaptive immunity (T cell subsets like Th1 CD4+ T cells, cytotoxic CD8+ T cells, Th2 cells, Th17 cells, Th9 cells), viral replication inhibitors, renin-angiotensin system inhibitors (Williams, 2021) and human recombinant soluble ACE2 (Abd El-Aziz et al., 2020), as well as heparin and glycosaminoglycan antithrombotics (Magnani, 2021), among others