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Aside from that, Enzymatic activity causes localized dark patches

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Another trial reported modest increases in sperm concentration after kisspeptin in men with low LH

*Correspondence: Gang Liu [email protected] These authors have contributed equally to this work This article was submitted to Animal Reproduction - Theriogenology, a section of the journal Frontiers in Veterinary Science ORCID: Shubin Li orcid.org/0000-0002-6865-9667 Jingyu Ren orcid.org/0000-0002-0048-3052 Wenqi Zhang orcid.org/0000-0003-4891-500X Yanfeng Dai orcid.org/0000-0001-7147-1748 Gang Liu orcid.org/0000-0002-5180-3765 Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Half of the participants took creatine (0.14 grams per kilogram of body weight of creatine, ~10 grams for a 160-pound female) daily for two years, while the other half took a placebo