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doi: 10.1093/cid/cix647 3 PatonJCTrappettiC

Electron transfer reactions in chemistry: theory and experiment (Nobel lecture)

Experimental verification showed that the inhibition of the mitochondrial ROS-mediated pathway enhances insulin production from pancreatic cells [88], subsequently causing ferroptosis due to the accumulation of lipid peroxides [89]

P., Heeren, R

Shao A, Hathcock JN

Furthermore, DAMPs released from compromised mitochondria, coupled with elevated ROS levels, serve to intensify immune responses, with microglia playing a pivotal regulatory role in this process (86)