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Recommended tools for assessing impulsivity include the Barratt Impulsiveness Scale, 19 Urgency-Premeditation-Perseverance-Sensation Seeking-Positive Urgency Behavior Scale, 20,21 Monetary Choice Questionnaire, 22 and Montreal Cognitive Assessment, 23 as well as relevant neuroimaging and laboratory evaluations (Table 2)

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The mouse was returned to the cage and a score was assessed on each bead until 20 min (intact marble = 0, partially buried = 1, buried but visible = 2, completely buried = 3)

doi: 10.1016/s1535-6108(03)00050-3 25

Through these mechanisms, as well as systemic glucose targeting to the brain, cerebral metabolism relies on alternative substrates (ketone metabolism) only when glucose availability is severely disrupted [58]

In the presence of 5, a time constant of = 41.4 min was determined (Fig