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One caveat was that participants in the mB12/LDFA and BH4 studies had significantly worse markers of glutathione metabolism and chronic oxidative stress at baseline, respectively

Despite these advances, KRAS inhibitors like sotorasib face resistance mechanisms primarily through the activation of bypass pathways such as autophagy and PI3K-AKT signaling

Process Biochem 95:186196

Drug Metab Dispos 48(10):10181027

Il a pour mission principale de protger nos cellules et leurs membranes cellulaires contre le stress oxydatif provoqu par les radicaux libres, ces molcules instables qui peuvent causer des dgts si elles ne sont pas neutralises