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The forefront research advancements reveal that the development of novel anti-tumor therapeutic strategies, based on the synergistic regulatory mechanism of mitophagy and ferroptosis and targeting the activation of the mitophagy pathway and the induction of ferroptosis, exhibits remarkable therapeutic potential in overcoming tumor drug resistance and inhibiting metastasis [11,12,13,14]

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Owing to the limitations and off-target side effects of antidiabetic drugs, exercise-induced control of hyperglycemia and increased insulin sensitivity is a preferred strategy to manage diabesity associated complications

As the previous Medical Director of Diabetes Center Community Hospital in Anderson Indiana, Dr