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MazloomiSNTalebiSMehrabaniSBagheriRGhavamiAZarpooshMet al

PUFAs, predominantly arachidonic acid (AA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA), are the main component of the neural cell membrane phospholipids

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These models, although evolutionary simple, are useful tools to enhance our understanding of the basic mechanisms underlying causal genes of AD and PD, protein-protein interactions between syn, A, and tau, and as a pharmacological screening approach

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In summary, while our study leverages the best available global data and standardized methods to quantify lead's contribution to AF, these limitations highlight the need for cautious interpretation