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GSH may aid in improving ischemic stroke pathogenesis by reducing cerebral infarction and preventing cell death (59)

Matrix metalloproteinase-10 is upregulated by thrombin in endothelial cells and increased in patients with enhanced thrombin generation

Some researchers also suggest glutathione can directly bind with the active site of tyrosinase (which contains copper), effectively inactivating the enzyme and further halting melanin synthesis

For instance, comparative analyses of different machine learning algorithms have shown that random forest models often outperform other approaches in predicting depression, with reported AUC values reaching 0.91 [207]

These metabolites function as regulators of epigenetic enzymes, thereby establishing a critical link between metabolism and epigenetics ( Fig

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