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873 The expression of ACSL4 and 4-HNE increase in the cartilage of OA patients and OA mice, while metformin increases p-AMPK and p-ACC levels in IL-1-treated chondrocytes, reverses ACSL4 and 4-HNE positive chondrocytes and OA lesions, and improves the ferroptosis sensitivity of chondrocytes through the AMPK/ACC pathway

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Metabolic CODEPENDENCIES IN THE TUMOR MIcroenvironment

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[DOI] [PMC free article] [PubMed] [Google Scholar] 147.Gozzetti, A

gcs-1 RNAi did not increase the tbb-6::GFP expression (Supplementary Fig