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A threshold level of glutathione has been shown to be necessary for pro- duction of the phytoalexin camalexin and also to de- termine pathogen resistance (Parisy et al., 2007)

6 Potential mechanisms of SIN in treating cerebral ischemia through the bone-brain Axis Recent studies have indicated that there is bidirectional regulation between the bone and the brain, with communication occurring through inflammatory mediators, bone metabolic products, and the endocrine system