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Phytoalexins from crucifers: synthesis, biosynthesis, and biotransformation

40 , 41 Given that even on the same dose of substrate precursor in loading tests there is a big variation in the amount of TMAO and TMA excretion, it is possible that the nature of the gut microflora may play a significant role in the generation of symptoms in some individuals

It is a non-essential nutrient, meaning that it can be synthesized by the body and does not have to be obtained from the diet

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Reduced expression of TRH in the hypothalamus appears to play a key role in the prolonged phase of critical illness, although the processes that trigger this upstream disturbance are somewhat unclear