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Description

Fibrosis induction significantly increased hepatic gene expression of COL1A1, -SMA, PDGFRB, and TIMP1 , elevated hepatic enzymes, increased histopathological findings, and increased collagen deposition as determined by Masons trichrome staining

10.1111/jfbc.14153 113 WangH

Tirzepatide, which is formulated as a once-weekly subcutaneous injection, stimulates two incretin receptors: GLP-1 receptors and glucose-dependent insulinotropic polypeptide (GIP) receptors