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Chemical bonds within the molecule gradually break down, reducing the active pharmaceutical ingredient (API) concentration

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Ceftriaxone intramuscular solutions remain stable (loss of potency less than 10%) for the following time periods: Ceftriaxone intravenous solutions, at concentrations of 10, 20 and 40 mg/mL, remain stable (loss of potency less than 10%) for the following time periods stored in glass or PVC containers: * Data available for 10 to 40 mg/mL concentrations in this diluent in PVC containers only